<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
3121-O269FJN 3121-O269FJN Argentina 2008 HIV1 B PBMC None

Treatment History
Order Regimen Weeks
1 NNRTI|NRTI|PI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V   Y188L   V35T, I47F, S48Q, V106I, I135V, R211K  
>3121-O269FJN| codons 1-212
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKFQKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLLVGSDLEIGQHRTKIEELRQHLLKW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12E, K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72S, L89M  
>3121-O269FJN| codons 8-99
RPLVEIRVEGQLMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDNILIEIC
GHKASGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Aulicino, PC Longitudinal analysis of HIV-1 BF1 recombinant strains in vertically infected children from Argentina reveals a decrease in CRF12_BF pol gene mosaic patterns and high diversity of BF unique recombinant forms. Infect Genet Evol, 2011