Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pt10 | Pt10w32 | Italy | 2010 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RAL|RTI | 35 |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| G140S, Q148H | S24N, D41N, L74I, A91T, L101I, T125A, V201I, Q216H, N254S |
| >Pt10w32| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMANDFNLPPVVAKEIVASCNKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIIIVAVHVASGYIEAEVIPTETGQETAYFILKLAGRWPVKTIHTDNGSN FTSTAVKAACWWAGIKQEFSIPYNPQSHGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKHITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDSSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
References
| Author | Title | Citation |
| Canducci, F | Cross-resistance profile of the novel integrase inhibitor Dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir. | J Infect Dis, 2011 |