<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pt1 Pt1W48 Italy 2010 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 RAL|RTI 43

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
E138A, G140S, Y143H, Q148H   L101I, S119R, K156N, I208L, G277R  
>Pt1W48| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGRN
FTSTTVKAACWWAGIKQAFSIPHNPQSHGVVESMNNELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDLQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMARDDCVASRQDED

References
Author Title Citation
Canducci, F Cross-resistance profile of the novel integrase inhibitor Dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir. J Infect Dis, 2011