<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V32G, I47M T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, K55R, Y59H, L63H, H69K, L89M  
>CY265| codons 1-99
PQITLWQRPLVAVRIEGQLIEALLDTGADDTGLEDINLPGKWKPKMMGGIGGFIRVRQHD
QIHIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I31M, V35T, T39*, K43R, V60I, K102Q, I135R, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245E, D250E, K281R, T286A, E291D, I293V, E297K, S322T, I326V, G335D, R356K, M357R, G359S, A360T, T369A, A371V, I375A, T377L, V381I, K390R, Q394T, A400T, T403M, E432D, V467I, T470S, D471E, Q480Y, H483Q, L491S, Q509H, K512R, L517M, S519N, Q524K, K527E, E529N, A534S, A554S  
>CY265| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKMKALTEIC*EMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDVVPLTKEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRST
HTNDVKQLAEVVQKAALESIIIWGKTPKFRLPITKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVISLSETTNQKTELY
AIQLALQDSGSEVNIVTDSQYALGIIQAHPDRSESEMVNQIIEKLIEKNKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, S24N, L28I, L101I, K111T, T112V, S119G, T122I, T124N, T125A, G134N, I135V, K156N, E157Q, V201I, T206S, I208L, L234I S283G
>CY265| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMANDFNIPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVTVIHTDNGGN
FISNAVKAACWWANVKQEFGIPYNPQSQGVVESMNNQLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDLQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011