Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CY255 | CY255 | Cyprus | 2009 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| V31I, I72V, L74I, I89L, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, M154I, D167E, V201I, L234I, S255N |
| >CY255| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVIIVAVHVASGYIEAEVLPAETGQETAYFLLKLAGRWPVKVVHTDNGPN FTSNAVKAACWWANIQQEFGIPYNPQSQGVVESINKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNNDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14KR, I15IV, E35D, M36I, R41K, L63LP, H69K, L89M, I93L |
| >CY255| codons 1-99 PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, E36D, T39M, K122E, D123S, I135T, S162SN, K173A, Q174RS, D177E, T200I, Q207A, R211S, V245E, E248D, D250DGNS, A272P, V276I, K277R, T286A, E291D, V292I, I293V, P294T, D324E, I326V, G335D, R356K, M357R, R358G, G359S, E370A, A371V, I375V, A376T, T377M, K390R, T403M, V435A, L452A, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554Q |
| >CY255| codons 1-560 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTDICMEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRASNPEIVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPDKSSWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKELVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRGSA HTNDVKQLTAVVQKVTMESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKAGKAGYVTDRGRQKVVPLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNKIIEKLIEKERVYLSWVPAHK GIGGNEQVDKLVSQGIRKVL |
References
| Author | Title | Citation |
| Kousiappa, I | Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. | ARHR, 2011 |