Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CY243 | CY243 | Cyprus | 2009 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, G16E, L19I, E35D, M36I, K45R, R57K, L63T, H69K, L89M | K14D |
| >CY243| codons 1-99 PQITLWQRPIVTVDIEGQIKEALLDTGADDTVLEDINLPGRWKPRMIGGIGGFIKVKQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, V60I, K102Q, D121H, K122E, I135T, S162CG, T165TI, K173ST, Q174K, D177E, I178IL, V179VI, T200A, Q207A, R211S, V245EQ, D250E, A272P, T286A, E291D, V292I, I293V, S322A, G335D, M357K, G359S, T369A, A371V, I375V, T377M, K390R, A400L, T403M, E404D, E432D, V435M, D471E, Q480H, H483Y, L491S, S519N, Q524K, K527G, E529D, A534S, A554T, I556V, K558R |
| >CY243| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQGSMIKILEPFRTKNPELII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLAEVVQKVAMESIVIWGKTPKFRLPIQKETWELWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPIMGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEKLIGKDKVYLSWVPAHK GIGGNEQVDKLVSTGVRRVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, V32I, D41N, I60V, I72V, T112V, I113V, T124A, T125A, G134N, K136Q, D167E, F181Y, V201I, I208L, T218I, L234I | S283G |
| >CY243| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIIAKEIVASCNKCQLKGEAMHGQVDCSPGV WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV YIHNFKRKGGIGGYSAGERIIDIIATDLQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Kousiappa, I | Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. | ARHR, 2011 |