Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CY232 | CY232 | Cyprus | 2008 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| L68V | S17N, I72V, I113V, T124N, T125V, G163E, T210I, K211R, D256E |
| >CY232| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHVEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN FTSNVVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIEQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQIRELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T4S, N37T, R41K, R57K, A71V, I93L |
| >CY232| codons 1-99 PQISLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMTLPGKWKPKMIGGIGGFIKVKQYD QILIEICGHKVIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| A98S, D123E, E138A, I142V, K173R, Q207L, R211K, V245E, A272P, T286A, P294S, E297K, L310I, G333E, V365I, A376S, S379G, T386I, D460N, K465R, H483Y, A534T, A554T |
| >CY232| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRLHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVISLTKEAE LELAENREIIKEPVHGVYYDPSKDLIAEIQKQEQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDIKQLTEAVQKISTEGIVIWGKIPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQRVVSLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLTWVPAHK GIGGNEQVDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Kousiappa, I | Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. | ARHR, 2011 |