<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, N37ND, R41RK, L63H, H69K, L89M, I93L  
>CY228| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QIHIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, K102KR, K122E, D123S, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, D250E, A272P, K277R, E291D, I293V, P294S, L310I, Q334H, G335D, R356K, G359T, V365I, A376S, T377M, K390R, A400T, E404D, E413D, L452I, R463K, V466I, V467I, D471E, H483Q, L491S, A508G, E516D, S519N, K527R, K530R, A534S, A554K A98AV
>CY228| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPVGLKRKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVSLTEEAE
LELAENREIIKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDIKQLTEAVQKISMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPDWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTDRGKQKIISLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQGQPDKSESDLVNQIIEQLIRKERVYLSWVPAHK
GIGGNEQVDKLVSKGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, S24D, D25E, L28I, P30A, S39C, M50I, I72V, L101I, T112V, I113V, T124A, T125A, K136Q, F181L, V201I, T218I, L234I, D278A S283G
>CY228| codons 1-288
FLDGIDKAQEEHERYHSNWRAMADEFNIPAVVAKEIVACCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVVHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
LIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011