<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  T97A S17N, V31I, I60V, I72V, T112V, T124S, T125A, V126L, G134D, I135V, V201I, E212Q, T218S, L234I, D256E S283G
>CY223| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGV
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQEAAYFLLKLAGRWPVKVIHTDNGSN
FTSSALKAACWWADVKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKQLQKQISKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, T12R, I13V, K14T, G16E, K20I, E35N, M36I, R41K, R57K, H69K, K70R, L89M  
>CY223| codons 1-99
PQITLWQRPIVRVTIEGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39N, K43E, D121H, K122E, I135T, E169D, K173A, Q174K, D177E, I178M, T200A, I202V, Q207N, R211K, V245Q, E248D, L283I, I293V, P294T, V317A, S322A, I326V, G335D, F346H, R356K, M357R, G359S, V365I, K366R, T369V, T377Q, S379G, T386V, K390R, T403M, K431R, V435A, R461K, T470N, D471E, Q480H, H483Y, L491S, K512R, A534S, A554N  
>CY223| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPEMVI
YQYMDDLYVGSDLEIGQHRAKVEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGTKALTEVVTLTEEAE
LELAENREILKEPVHGAYYDPAKDLVAEIQKQGQDQWTYQIYQEPHKNLKTGKYAKRRSA
HTNDIRQLVEAVQKIAQEGIVIWGKVPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEREPIAGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLNETTNQKTELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVSQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011