<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  Q95K, G140E V32I, E35K, K42R, G70E, L101I, T112I, T124G, T125A, K136Q, M154I, E157K, R166K, V201I, L234I, D256E, V260I E152K, S283G
>CY222| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVIAKKIVASCDRCQLKGEAMHGQVDCSPGI
WQLDCTHLEEKIILVAVHVASGYIEAEVIPAETGKETAYFILKLAGRWPVKIIHTDNGSN
FTSGAVKAACWWAGIQQEFEIPYNPQSQGVVKSINKKLKKIIGQVKDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSEIKVIPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12V, I13V, I15V, E35D, M36I, R41K, K43R, R57K, L63T, E65D, I72T, L89M  
>CY222| codons 1-99
PQITLWQRPVVVVKVGGQLKEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVKQYD
QITIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, D123E, I135L, K173V, Q174K, T200I, Q207A, R211K, V245Q, E248D, A272P, V276I, K277R, T286A, E291D, V292I, I293V, E297A, I326V, F346C, R356K, G359S, A376V, T377Q, T386I, E396K, W402*, T403I, E404D, K431T, V435T, A446S, L452I, D471E, T477A, L491S, Q524R, K527Q, A534S, G543R, A554N, V559I E302K
>CY222| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPDIVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTDIVPLTAEAE
LKLAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPCKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIVQESIVIWGKIPKFKLPIQKKTWEAW*IDYWQATWIPEWEFVNTP
PLVKLWYQLETEPITGAETFYVDGASNRETKIGKAGYVTDRGRQKVVSLTETTNQKAELQ
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVSQIIERLIQKEKVYLSWVPAHK
GIRGNEQVDKLVSNGIRKIL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011