<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63S, H69Q, V77I, L89M  
>CY212| codons 1-99
PQITLWQRPVVTIRIGGQLKEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVKQYD
NISIEICGQKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V35T, T39A, K49R, D123E, S134C, I135V, S162C, P170S, K173T, Q174K, D177N, T200I, Q207E, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, E297T, I329L, R356K, G359T, T377M, Q394L, E399D, A400T, Q428H, K431T, V435A, A446S, L452Q, R461K, V466A, D471E, T477A, H483K, A554T  
>CY212| codons 1-560
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPCVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILESFRTKNPNIVI
YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIAMESIVIWGKTPKFKLPILKETWDTWWTEYWQATWIPEWEFVNTP
PLVKLWYHLETEPIAGAETFYVDGASNRETKQGKAGYVTDKGRQKAVSLTETTNQKAELQ
AIKLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSTGIRKVL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011