<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, R20K, V31I, I60M, I72V, L74I, T112V, I113V, S119T, T124A, T125A, V126F, G134S, K136Q, V201I, L234I S283G
>CY207| codons 1-288
FLDGIDKAQEDHEKYHSNWKAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGM
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGTN
FTSAAFKAACWWASIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, R57K, I62IV, L63P, H69K, L89M  
>CY207| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYD
QVPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, V60I, K102Q, K122E, D123N, S134SR, K173G, Q174K, D177E, V179I, Q197L, T200A, Q207A, R211N, D237DE, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, I341F, M357K, G359S, T369A, A371V, I375M, A376S, T377M, K390R, A400T, T403R, E404D, E432D, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, I556V P25PS
>CY207| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWSLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPRINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRGKNPEIII
YQYMDDLYVGSDLEIGLHRAKIEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPEKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQFYQEPFKNLKTGKYARKRSA
HTNDVKQLAEVVQKMSMESIVIWGKTPKFRLPIQKETWETWWRDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIGKDKVYLSWVPAHK
GIGGNEQVDKLVSSGVRKVL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011