<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  Q95K D6H, E11Q, K14R, R20K, S24I, D25E, V32I, L63I, L74I, A91E, F100Y, L101I, T112V, S119P, T125A, K136Q, V201I, T218S, I220V, N222K, L234V S283G, R284G
>CY203| codons 1-288
FLDGIHKAQEQHERYHSNWKAMAIEFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQIDCTHLEGKIIIVAVHVASGYIEAEVIPEETGKETAYYILKLAGRWPVKVIHTDNGPN
FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQISKVQKFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGGQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16GR, L19IMR, E21EK, E34EK, M36I, R41K, K55KR, L63A, H69K, V82VI, I93L  
>CY203| codons 1-99
PQITLWQRPLVSIKVRGQRKKALLDTGADDTVLKEINLPGKWKPKMIGGIGGFIRVRQYD
QIAIEICGKKAIGTVLVGPTPINIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39E, S48T, V60I, V118I, K122A, D123NS, I135T, E138A, T139A, K173A, Q174R, D177E, V179VI, G196GE, T200A, R211KQ, F214L, V241I, V245Q, A272S, K277R, T286A, E291D, Q334N, G335D, R356K, G359T, T377L, V381I, K390R, T403A, E404D, V435A, L452M, S468P, D471E, H483Y, L491S, S519N, K527Q, K530R, A534S, D549N, A554N Q207*DEY, Q269Q_INWASQ
>CY203| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DASFRKYTAFTIPSTNNAAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIII
YQYMDDLYVGSDLEIEQHRAKIEELRYHLLQWGLTTPDKKHQKEPPFLWMGYELHPDKWT
IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIALESIIIWGKTPKFRLPIQKETWEAWWADYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDRGRQKVVPLTETTNQKTELQ
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIQKERVYLSWVPAHK
GIGGNEQVNKLVSNGIRKVL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011