<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, L28P, V31I, M50L, I72V, L74I, T124A, V201I, T206S S283G, D286N
>CY200| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNPPPIVAKEIVASCDKCQLKGEALHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSATVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQNED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K14R, G16E, K20I, M36I, P39S, R41K, I62K, H69Q, L89M  
>CY200| codons 1-99
PQITLWQRPIVTVRIEGQLIEALLDTGADDTVLEEINLSGKWKPKMIGGIGGFIKVRQYD
QKLIEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35M, T39A, S48E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, E297A, S322T, I326V, Q334P, G335D, R356K, M357R, G359S, T369A, I375V, A376T, S379C, K390R, A400S, E432D, D471E, Q480H, H483Y, L491S, Y501D, A534S, V548I, A554S, K558R  
>CY200| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAEMEKEGKIEKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTAEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGPDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLAEAVQKVTTECIVIWGKTPKFRLPIQKETWESWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIYLALQDSGSEVNIVTDSQDALGIIQAQPDKSESELVSQIIEQLIKKEKVYLSWVPAHK
GIGGNEQIDKLVSSGIRRVL

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011