Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CY194 | CY194 | Cyprus | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, S24N, V31I, L45V, I72V, T112A, S119P, T124N, M154L, A196T, V201I, K211R |
| >CY194| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMANDFNLPPIVAKEIVASCDKCQVKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKAIHTDNGPN FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESLNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSTGERIIDIIATDIQTRELQKQITKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32M | Q7R, V11G, E35D, N37D, A71T, I72V |
| >CY194| codons 1-99 PQITLWRRPLGTIKIGGQLKEALLDTGADDTMLEDMDLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKTVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K104R, R211K, V292I, I293V, S322T, R356K, K390R, E399D, E449D, D460N, R461K, S468N, Q524E, A554T, K558R |
| >CY194| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKMRGA HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWDAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRDTKLGKAGYVTNKGRQKVVNLTDTTNQKTELQ AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEELIKKEKVYLAWVPAHK GIGGNEQVDKLVSTGIRRVL |
References
| Author | Title | Citation |
| Kousiappa, I | Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. | ARHR, 2011 |