<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I L10I, T12E, I13V, K20I, M36I, R41K, L63P, C67Y, H69K, K70R, I72V, L89M  
>CY192| codons 1-99
PQITLWQRPIIEVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEIYGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11S, V35T, T39A, V60I, K104R, K122E, D123S, I135T, K173A, D177E, T200A, Q207EG, R211K, F214L, V245Q, E248D, K281R, E291D, V292I, I293V, P294T, E297K, S322E, D324E, G335D, R356K, M357R, G359S, K366R, T369A, A371V, K374R, I375V, A376T, K390R, A400T, T403M, A446S, V467I, D471E, T477A, Q480H, G490E, K512R, L517V, S519N, Q524K, K527E, K530R, A534S, A554S  
>CY192| codons 1-560
PISPIETVPVSLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDIVTLTKEAE
LELAENREILKEPVHGVYYDPEKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVRQLAEVVQRVTTESIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGASNRETKLGKAGYVTDRGRQKVISLTETTNQKAELH
AIHLALQDSELEVNIVTDSQYALGIIQAQPDRSESEVVNQIIEKLIEKERVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K7R, V31I, I72V, T112V, T124A, T125A, V126M, G134D, I135V, D167E, V201I, T206S, L234I S283G
>CY192| codons 1-288
FLDGIDRAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAMKAACWWADVKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Kousiappa, I Molecular characterization of HIV type 1 strains from newly diagnosed patients in Cyprus (2007-2009) recovers multiple clades including unique recombinant strains and lack of transmitted drug resistance. ARHR, 2011