<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, K42Q, I84M, L101I, T112V, T124S, T125A, G134S, K136R, M154I, E157K, V201I, T206S, L234I, R269K, D278A S283G
>CN0358| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDQCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYMEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN
FTSSAVKAACWWASIRQEFGIPYNPQSQGVVESINKKLKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, K14R, R41K, D60E, L63A, I64V, V77L, I93L  
>CN0358| codons 9-99
PLVPIRIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYEQIAVEICG
HKAIGTVLLGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, E40K, G45E, S48T, V60I, D121Y, K122E, R211K, V245Q, E248Q, A272P, K277R, E291D, V292I, I293V, V317I, D324E, G335D, R356K, G359T, K366R, T377M, K390R, A400T, E404D, E432D, V435A, A437V, E438K, L452I, Q464K, D471E, H483Y, L484I, L491S, S519N, A534S, G541K, E546K, A554S E29K, G273E, S379N
>CN0358| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEKKIKALTAICEKMEKEEKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPQKDSWTVNDIQKLVGKLNWASQIYPEIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGIYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVRQLTEAVQKIAMENIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGVKTFYVDGAANRETKIGKAGYVTDRGRKKVVSLTETTNQKTELQ
AIYIALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK
KIGGNKQVDKLVSSGIRKVL

References
Author Title Citation
Zeng, H Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China. ARHR, 2012