<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, L19M, E35D, M36I, R41K, R57K, L63S, H69K, L89M  
>CN1400| codons 1-99
PQITLWQRPLVTVKIGGQMKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, V35T, T39K, K43A, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, F214L, I244V, V245E, E291D, V292I, I293V, E312T, H315Q, D324E, I326V, I329V, G335D, P345Q, F346Y, M357K, G359S, A360T, K366R, A371V, A400T, E432D, V435I, G436E, D460N, D471E, Q480H, H483Y, L491S, E492K, K512R, L517I, S519N, Q524E, I526V, A534S, A554S N265K
>CN1400| codons 1-560
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEAEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPVELPEKDSWTVNDIQKLVGKLKWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKTPVQGVYYDPSKELVAEVQKQGQDQWTYQIYQEQYKNLKTGKYARKRST
HTNDVRQLTEVVQKIATESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIEAETFYVDGAANRETKLGKAGYVTNRGRQKVVSLTETTNQKTELH
AIYLALQDSGSKVNIVTDSQYALGIIQAQPDRSESEIVNQIIEELVKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, A23V, D25E, V31I, T112V, T124A, T125A, C130G, G134N, I135V, K136R, V165I, V201I, L234I S283G
>CN1400| codons 1-288
FLDGIDKAQEEHERYHSNWRTMVSEFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAAGWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQIRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Zeng, H Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China. ARHR, 2012