<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, A21T, S57G, Q95R, L101I, T125M, I135V, I162V, D167E, V201I, L234I S283G, Q285P
>CN1300| codons 1-288
FLDGIDKAQEDHEKYHSNWRTMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCGPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGRETAYFILKLAGRWPVKTIHTDNGSN
FTSTMVKAACWWAGVKQEFGIPYNPQSQGVVESMNKELKKIVGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRPDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, E35D, M36I, R41K, H69K, L89M  
>CN1300| codons 1-99
PQITLWQRPLVTIKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179E E6D, V21A, V35T, T39K, K43E, K122E, D123S, I135R, R211K, F214L, T240A, V245A, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, V381I, K385R, K388R, K390R, A400T, D460N, R461K, I482T, H483C, L491S, S519N, K527N, K530R, A554S G99R
>CN1300| codons 1-560
PISPIDTVPVKLKPGMDGPKAKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPARLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIEI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWA
VQPIALPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLTEVVQKIATESIIIWGRTPRFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVSLTDTTNQKTELQ
ATCLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERVYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Zeng, H Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China. ARHR, 2012