Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1518 | UK1518 | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ NFV+ AZT | 68 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | V35T, E36A, T39E, S48T, K122E, D123S, I135T, S162NY, K173T, D177E, T200X, Q207K |
| >UK1518| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTQNPEIVI YQYVDDLYVGSDLEIGQHRXKIEELRKHLLRWGFTTPDKKHQKEPPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | T12S, I15V, L19V, K20T, E35D, M36I, N37NS, R41K, H69K, T74S, L89M, I93L |
| >UK1518| codons 1-99 PQITLWQRPLVSIKVGGQVTEALLDTGADNTVLEDISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRDMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |