<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  L74M K14R, A21T, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, K211R, L234I, V259I S283G
>CN0918| codons 1-288
FLDGIDKAQEEHERYHSNWRTMASDFNLPPVIAKEIVANCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIMVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKIVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20R, M36I, N37I, R41K, H69K, L89M, I93L  
>CN0918| codons 1-99
PQITLWQRPLVTVRIGGQLREALLDTGADDTVLEEIILPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, V35T, T39R, K122E, D123N, I135L, S162C, K173I, Q174K, D177E, T200I, Q207N, R211S, K238R, V245A, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, A355G, M357K, G359S, K366R, A371V, T386I, K390R, K395R, A400T, E432D, Q464K, D471E, Q480Y, I482V, H483Y, L491S, A502V, K512R, L517V, S519N, Q524E, V531I, A534S, A554S  
>CN0918| codons 1-560
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRIKIEELRNHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIALPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYGRKRSA
HTNDVRQLTEVVQKIATESIVIWGKIPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRKKVVSLTETTNQKTELY
AVYLALQDSGSEVNIVTDSQYVLGIIQAQPDRSESEVVNQIIEELIKKEKIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Zeng, H Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China. ARHR, 2012