Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1447 | UK1447 | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ IDV+ 3TC | 39 |
| 2 | EFV+ AZT+ ABC | 43 |
| 3 | DDI+ RTV+ SQV | 44 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48GA, I54V, V82A, I84V, L90M | L23LI, K43KT | L10Y, I15V, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89LM, I93L |
| >UK1447| codons 1-99 PQITLWQRPYVTIKVGGQLKEAILDTGADDTVLEEINLPGKWTPKMIAGIGGFVKVRQYD QVVIEICGKKVIGSVLVGPTPANVIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V, T215Y | K219R | K103N | P225H | V35T, T39E, S48T, K122E, D123S, I135L, K173T, Q174K, T200A, Q207E, R211RK, L228R |
| >UK1447| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDRKHQKEHPFRWMGYEL |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |