<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I13V, E35D, M36I, R41K, L63H, H69K, L89M  
>CN0892| codons 1-99
PQITLWQRPLVPVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIHIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V10I, V35T, T39K, K43E, S48P, K122E, D123N, K173M, Q174K, D177E, I178M, T200I, Q207A, R211S, V245E, K259E, K281R, T286A, E291D, V292I, I293V, E297K, L301I, R307K, E308R, I309V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376T, K390R, A400T, E432D, V435E, N447S, S468H, D471E, Q480H, H483Q, L491S, I505V, K512R, L517V, S519N, E523G, Q524E, A534S, A554S G273R, G316R, Y342H
>CN0892| codons 1-560
PISPIDTVPIKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKIPKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRMKNPEMVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQELVGKLNWASQIYARIKVKQLCRLLRGAKALTDIVPLTKEAE
IELAENKRVLKTPVHRVYYDPSKDLVAEVQKQGQDQWTYQIHQEPFKNLKTGKYARKRSA
HTNDVRQLVEVVQKVTTESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIEGAETFYVDGAASRETKLGKAGYVTDRGRQKVVHLTETTNQKTELH
AIQLALQDSGSEVNIVTDSQYALGVIQAQPDRSESEVVNQIIGELIKKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  G163K K14R, A21T, A23V, N27G, V31I, S39N, L45I, I72V, K103R, T112V, T124A, T125A, G134N, I135V, K136R, K160N, D167E, V201I, L234I, D253E W243R, S283G
>CN0892| codons 1-288
FLDGIDKAQEEHERYHSNWRTMVSDFGLPPIVAKEIVANCDKCQIKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLRLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKNIIKQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLRKGEGAVVIQENSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Zeng, H Emergence of a new HIV type 1 CRF01_AE variant in Guangxi, southern China. ARHR, 2012