Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1436 | UK1436 | U.K. | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ NVP+ AZT | NA |
| 2 | SQV+ RTV+ 3TC+ D4T | NA |
| 3 | D4T+ 3TC+ NFV | 123 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N83D | I13V, K14R, K20R, A22V, E35D, M36I, R41K, R57K, H69K, L89I, T91A |
| >UK1436| codons 1-99 PQITLWQRPLVTVRIGGQLREVLLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVDIIGRNILAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181V | E6D, V21I, V35T, V60I, R83K, K122E, D123S, K173S, Q174K, D177E, I178L, V179I, T200A, Q207E, R211K, H221Y |
| >UK1436| codons 1-234 PISPIDTVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPELII VQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKYQKEPPFLWMGYEL |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |