Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1428a | UK1428a | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ D4T+ DDI | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | T27S, V35K, T39E, E42K, K122E, D123S, I135R, S162A, E169D, K173A, D177E, T200A, Q207E, H221Y |
| >UK1428a| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALKEICEEMKKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILDPFRAQNPEIVI CQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKYQKEPPFLWMGYEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | I15V, L19I, M36I, N37S, R41K, H69K, T74S, L89M, I93L |
| >UK1428a| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKIIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |