Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1154 | UK1154 | U.K. | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | NA |
| 2 | NFV+ 3TC+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | T12S, I13V, I15V, L19I, K20T, E35D, M36I, R41K, D60E, L63P, I64V, H69K, V82I, L89M, I93L |
| >UK1154| codons 1-99 PQITLWQRPLVSVKVGGQITEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QIPVEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | V8I, V35T, T39E, K122E, I135T, A158S, K173A, Q174R, D177E, I178M, T200A, Q207E, R211Q |
| >UK1154| codons 1-226 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRARNPEMVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLQWGFYTPDKKHQKEPP |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |