Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK1147 | UK1147 | U.K. | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ 3TC+ AZT | 34 |
| 2 | 3TC+ D4T+ IDV | 47 |
| 3 | DLV+ ABC+ NFV | 70 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | K43T | T12S, I15V, L19I, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, H69K, A71T, L89T, I93L |
| >UK1147| codons 1-99 PQITLWQRPLVSIKVGGQITEALLDTGADDTVLEDIDLPGRWTPKIIGGIGGFIKVRQYE EIPIEICGKKTIGTVLVGPTPVNIIGRNTLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215Y | M230L | V35T, E36A, T39D, V60I, V90I, K173T, Q174K, I178L, E203D, Q207E |
| >UK1147| codons 1-237 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDLVI YQYVDDLYVGSDLEIGQHRTKIDELREHLLRWGFYTPDKKHQKEPPFLWLGYELHPD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |