<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
UK1125 UK1125 U.K. 2000 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NVP+ DDI+ D4T 139
2 3TC+ AZT+ IDV+ RTV 15

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, Q18X, L19T, M36I, R41K, L63P, H69K, I93L  
>UK1125| codons 1-99
PQITLWQRPLVSIKVGGXTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K101E, Y181C   V35T, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, Q174R, D177E, T200A, Q207E, R211K  
>UK1125| codons 1-226
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRARNPEIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPP

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005