Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| UK496b | UK496b | U.K. | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ D4T+ DDI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | T12S, I13V, L19I, K20T, M36I, R41K, D60E, L63P, I64V, H69K, L89M, I93L |
| >UK496b| codons 1-99 PQITLWQRPLVSVKIGGQITEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QIPVEICGKKAIGTVLVGPTPVNIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| G190GR | V35T, E36A, T39D, K122E, K173T, D177E, Q197R, T200V, Q207N, R211K | P150PA |
| >UK496b| codons 1-227 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLAQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVRSDLEIGRHRVKIEELRNHLLKWGFTTPDKKHQKEPPF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |