<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
UK449 UK449 U.K. 1999 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ SQV+ D4T+ DDC+ RTV NA
2 NVP+ 3TC+ AZT NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
L90M L23I T12S, L19I, E35D, M36I, R41K, D60E, L63S, H69K, V82I, L89M, I93L, L97X  
>UK449| codons 1-99
PQITLWQRPLVSIKIGGQIKEAILDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QISIEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTXNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005