Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BE40 | BE40 | Belgium | 2000 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 15 |
| 2 | AZT+ DDC+ SQV | 75 |
| 3 | 3TC+ SQV+ D4T | 33 |
| 4 | DDI+ IDV+ D4T | 35 |
| 5 | IDV+ 3TC+ D4T+ NVP | 25 |
| 6 | NVP+ D4T+ NFV+ 3TC | 68 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10I, I15V, K20M, R41K, D60E, I62V, L63P, A71T, I72V, V75I, L89M, I93L |
| >BE40| codons 1-99 PQITLWQRPIVTIKVGGQLMEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYE QVPIEICGHKTVGTILVGPTPVNIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | Y181C | V108I | V35T, K49R, V60I, T69N, K122E, D177E, Q207E, P243T, V245K, D250E |
| >BE40| codons 1-259 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIKLPEKESWTVNDIQK |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Snoeck, J | Rising prevalence of HIV-1 non-B subtypes in Belgium: 1983-2001. | JAIDS, 2004 |