<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BE26 BE26 Belgium 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT 106
2 3TC+ NVP+ AZT 95

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E35D, M36I, N37D, R41K, R57K, H69K, T74S, L89M  
>BE26| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y188YC   E6D, T7A, V35T, V60I, K103Q, K122E, D123S, I135T, F171Y, K173AS, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, P294T, E312DG, G335D I63V
>BE26| codons 1-341
PISPIDAVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAVKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKQKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPYRSKNPEIII
YQYVDDLCVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKGPVHGVYYDPSKDLIAEIQKQGQDQWTYQI

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Snoeck, J Rising prevalence of HIV-1 non-B subtypes in Belgium: 1983-2001. JAIDS, 2004