<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E10D, K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, D253E S283G
>05TH130087| codons 1-288
FLDGIDKAQDEHERYHSNWRTMASDFNLPPVVAKEIVANCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQIREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQENSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12I, I13V, G16E, E35D, M36I, R41K, L63N, H69K, L89M, I93L  
>05TH130087| codons 1-99
PQITLWQRPVVIVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QINIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V8I, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135T, E169D, Q174R, I178M, G196E, Q207A, R211S, K238R, V245K, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, T386I, K390R, A400T, T403M, E432D, S468A, T470N, D471E, Q480H, L491S, L517I, S519N, Q524E, E529D, A534S, Q547K, A554S  
>05TH130087| codons 1-560
PISPIDTIPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKRNPDMVI
YQYMDDLYVGSDLEIEQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVRQLTEVVQKIATESIVIWGKIPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVALNETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEELIKKDKVYLSWVPAHK
GIGGNEKVDKLVSSGIRKVL

References
Author Title Citation
Kijak, GH HIV-1 prevalence and subtype distribution in HIV-1 positive volunteers deferred from enrollment in a phase III prime-boost HIV-1 vaccine trial in Thailand J Virol, 2013