Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-23 | TCDD-23_1 | Zimbabwe | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ DDC+ AZT | 205 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, L19I, M36I, R41K, D60E, L63P, H69K, V82I, L89M, I93L |
| >TCDD-23_1| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QIPIEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | D67G, K219Q | V35T, T39E, S48T, K64N, V90I, K122E, D123S, E138A, K173T, Q174K, T200A, E203K, Q207E, R211K, F214L, L228R, V245E, E248D |
| >TCDD-23_1| codons 1-258 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAINKKGSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYMDDLYVGSDLEIGQHRAKIKELREHLLKWGLTTPDQKHQKEPPFRWMGYELHPDKWT VQPIELPDKDSWTVNDIQ |
References
| Author | Title | Citation |
| Kantor, R | HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy. | ARHR, 2002 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |