Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-35 | TCDD-35_1 | Zimbabwe | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC+NFV | 65 |
| 2 | 3TC+AZT+IDV | 18 |
| 3 | 3TC+AZT+NFV | 14 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70KR, M184V, T215Y | V35T, E36A, T39E, S48T, E53D, V60I, K122E, D123S, I135V, S162C, K166R, I167IV, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, L228H |
| >TCDD-35_1| codons 32-242 KALTAICEELEKEGKITKIGPDNPYNTPIFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQ LGIPHPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSVNNETPGIRYQYNVLPQ GWKGSPAIFQCSMTRVLEPFRAKNPELVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLK WGFYTPDKKHQKEPPFHWMGYELHPDKWTVQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G73S | T12S, I15V, L19I, M36I, R41K, D60E, L63AP, H69K, V75I, I93L |
| >TCDD-35_1| codons 3-94 ITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEQI AIEICGKKAISTILVGPTPVNIIGRNLLTQLG |
References
| Author | Title | Citation |
| Kantor, R | HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy. | ARHR, 2002 |