Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TCDD-26 | TCDD-26 | Zimbabwe | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ 3TC | 10 |
| 2 | AZT+ 3TC | 8 |
| 3 | 3TC+ AZT+ SQV | 28 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19X, M36I, R41K, L63V, H69K, V82I, L89M, I93L |
| >TCDD-26| codons 3-99 ITLWQRPLVTIKVGGQXKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQI VIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, K43R, S48ST, E53ED, K122E, D123NS, K173E, D177E, I178IM, T200A, E204EK, Q207EK |
| >TCDD-26| codons 26-244 LTEEKIKALTAICEEMEREGKITKIGPDNPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQ DFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQ YNVLPQGWKGSPAIFQSSMTKILEPFREQNPEMVIYQYMDDLYVGSDLEIGQHRAKIEKL REHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPI |
References
| Author | Title | Citation |
| Kantor, R | HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy. | ARHR, 2002 |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |