Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JF-9 | JF9-M6 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI | NA |
| 2 | D4T+ NFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | E44D, V60I, V118I, D123E, R211K |
| >JF9-M6| codons 1-243 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10I, E35D, M36V, N37S, R41K, K45Q, I62V, A71T |
| >JF9-M6| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADNTVLEDVSLPGKWKPQMIGGIGGFIKVRQYD QVLIEICGHKTIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Fitzgibbon, JE | Emergence of drug resistance mutations in a group of HIV-infected children taking nelfinavir-containing regimens. | ARHR, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |