<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SWC-0233 P0233-2920 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ EFV+ NFV 12
2 NFV 9
3 ABC+ APV+ D4T 38

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82T, L90M   L10V, K20R, M36I, L63P, A71V, I72V, I93L  
>P0233-2920| codons 1-99
PQITLWQRPVVTIKIGGQLREALLDTGADDTVLEEINLPGRWKPKIVGGIGGFVKVRQYD
QIPIEICGHKVVGTVLVGPTPTNIIGRNLMTQLGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003