Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CR_97ZA012 | CR_97ZA012 | South Africa | 1997 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, N37D, K43R, L63P, H69K, L89M, I93L |
| >CR_97ZA012| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDIDLPGRWRPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, E204D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E300K, I326V, Q334D, G335D, R356K, G359T, T377L, K390R, E399D, A400I, E404D, V435A, G436E, E449D, L452K, V466I, T470N, D471E, T477A, H483Q, S519N, E523G, K530R, V531I, A534S, A554S |
| >CR_97ZA012| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEDLRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAK LELAENREILKEPVHGVYYDPSKDLVAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWDIWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAEAETFYVDGAANRDTKKGKAGYVTDRGRQKIVSLNETTNQKAELQ AIQLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIGQLIKKERIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, D25E, V31I, V37I, M50I, I60V, I72V, I84M, A91G, F100Y, L101I, T112V, T124A, T125A, K136Q, I162V, I200M, V201I, T218I, L234I, R269K, D278A | S283G |
| >CR_97ZA012| codons 1-288 FLDGIDKAQEDHEKYHSNWRAMASEFNLPPIVAKEIIASCDKCQLKGEAIHGQVDCSPGV WQLDCTHLEGKVILVAVHVASGYMEAEVIPGETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIVGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERMIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Rodenburg, CM | Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents. | ARHR, 2001 |