<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PW_UG465 PW_UG465 Uganda 1998 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None 49

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, M36I, R41K, L63Q, I64V, I72V  
>PW_UG465| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIQVEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49KR, V60I, K122E, D123E, I142IV, D177E, I178M, G196E, T200TA, Q207E, R211K, V245K, D250E, L282C, L283I, T286A, I293V, P294X, E297R, A304E, D324DE, Q334E, G335D, P345Q, F346Y, R356K, M357S, A360T, E370A, I375V, T377Q, S379C, K390R, A400T  
>PW_UG465| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYMDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKCIRGAKALTEVVXLTREAE
LELEENREILKEPVHGVYYDPSKELIAEIQKQGEDQWTYQIYQEQYKNLKTGKYAKSRGT
HTNDVKQLTAAVQKVAQECIVIWGKTPKFRLPIQKETWET

References
Author Title Citation
Weidle, PJ Resistance to antiretroviral therapy among patients in Uganda. JAIDS, 2001