<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PW_UG460 PW_UG460 Uganda 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None 47

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, Q18QE, K20R, E35D, M36I, R41K, R57K, H69K, L89M  
>PW_UG460| codons 1-99
PQITLWQRPLVTVKIGGELREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, I47IF, S48T, V60I, K122E, D123S, I135T, S162FY, T165I, K173AS, Q174K, D177E, T200TA, Q207A, R211S, V245K, D250E, A272P, T286A, E291D, I293V, P294T, E312D, G335D, M357R, G359S, T369A, A371V, I375V, T377M, A400T V254VI
>PW_UG460| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKFTKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQFSMIKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTINDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVKQLAEVVQKVAMESIVIWGKTPKFKLPIQKETWET

References
Author Title Citation
Weidle, PJ Resistance to antiretroviral therapy among patients in Uganda. JAIDS, 2001