<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PW_UG4399 PW_UG4399 Uganda 1997 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, K20R, E35D, M36I, R41K, R57K, L63T, C67Y, H69K, L89M  
>PW_UG4399| codons 1-99
PQITLWQRPIVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QITIEIYGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K122E, D123S, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245Q, D250E, A272T, E291D, I293V, K311N, E312N, D320E, G335D, M357R, G359S, A360T, A371V, A376V, V381I, A400T  
>PW_UG4399| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGTKALTDVVPLTEEAE
LELAENREILNNPVHGVYYEPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRRST
HTNDVKQLTEVVQKIVTESIIIWGKTPKFKLPIQKETWET

References
Author Title Citation
Weidle, PJ Resistance to antiretroviral therapy among patients in Uganda. JAIDS, 2001