<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NY_M49 M49 France 2000 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     A98AG T27S, V35X, K43EQ, K49KR, S68G, D121Y, K122E, D123G, I135T, K166KR, K173I, Q174K, D177E, I195IL, G196E, E203EK, Q207A, R211S, F214L  
>M49| codons 16-239
MDGPKVKQWPLSEEKIKALXEICTEMEEEGKISRIGPENPYNTPVFAIKKKDGTKWRKLV
DFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPLYEGFRKYTAFTIPST
NNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEIVIYQYVDDLYVGSDLEL
EQHRTKIKELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, E35D, M36I, R41K, L63P, H69Q, V77VI, L89M  
>M49| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGQKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Yahi, N Use of drug resistance sequence data for the systematic detection of non-B human immunodeficiency virus type 1 (HIV-1) subtypes: How to create a sentinel site for monitoring the genetic diversity of HIV-1 at a country scale. J Infect Dis, 2001