<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
NY_M47 M47 France 2000 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ D4T NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, L19P, K20I, M36I, H69K, L89M  
>M47| codons 1-99
PQITLWQRPVVTVKIGGQPIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, M184V, T215F K219E     V35T, E36D, E40D, K49R, V60I, K102Q, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K  
>M47| codons 16-239
MDGPKVKQWPLTEEKIKALTDICTDMEKEGKISRIGPENPYNTPIFAIKKKNSTKWRKLV
DFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSV
NNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEMVIYQYVDDLYVGSDLEI
GQHRAKIEELREHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKW

References
Author Title Citation
Yahi, N Use of drug resistance sequence data for the systematic detection of non-B human immunodeficiency virus type 1 (HIV-1) subtypes: How to create a sentinel site for monitoring the genetic diversity of HIV-1 at a country scale. J Infect Dis, 2001