<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
J349 J349_PR_RT Brazil 2007 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V21I, V35T, T39M, S68G, D123E, S162C, E169D, K173A, Q174K, T200I, Q207A, R211K, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297T  
>J349_PR_RT| codons 1-301
PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICMEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI
YQYMDDLYVGSDLEIGQHRIKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE
L

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12N, I15V, E35D, M36I, R41K, R57K, Q61N, I72V, L89M D25DN
>J349_PR_RT| codons 1-99
PQITLWQRPLVNIKVGGQLKEALLNTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NILIEICGHKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Santos, AF Primary HIV-1 drug resistance in the C-terminal domains of viral reverse transcriptase among drug-naive patients from southern Brazil J Clin Virol, 2011