<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    I72V, T124A, M154I, I208L, K211R, E212I, Q216H, V260I  
>129473| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSATVKAACWWAGIKQEFGIPYNPQSQGVVESINKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDLQTRILQKHITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVIPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, L19I, N37S, R41K, K45R, D60DE, I64V, E65ED  
>129473| codons 1-99
PQITLWQRPLVTVKIGGQIKEALLDTGADDTVLEEMSLPGKWKPRMIGGIGGFIKVRQYE
QILVDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V108VI V60I, K122P, D123E, K166R, Q174E, D177E, Q207R, V245T, A272P, K277R, E291ED, I293V, E297A, I329V, Q334N, M357I, K388R, E396D, T403M, K431T, N447S, V467I, H483Y, L503I, K527N, A554T  
>129473| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DPEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKENPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRRHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDVVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGNGQWTYQIYQEPFKNLKTGKYARIRGA
HTNDVKQLTEAVQKIATESIVIWGKTPRFKLPIQKDTWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVISLTDTTNQKTELQ
AIYLALQDSGLEVNIVTDSQYAIGIIQAQPDKSESELVSQIIEQLINKEKVYLAWVPAHK
GIGGNEQVDKLVSTGIRKVL

References
Author Title Citation
Nadai, Y HIV-1 epidemic in the Caribbean is dominated by subtype B. PLoS ONE, 2009