Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, S24G, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I | S283G |
| >AA126a08L| codons 1-288 FLDGIDKAQEEHERYHSNWRTMAGDFNLPPIVAKEIVANCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G16E, E35D, M36I, R41K, D60E, H69K, L89M, I93L |
| >AA126a08L| codons 1-99 PQITLWQRPLVTIKVEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11A, V21I, V35T, T39K, K43E, K101R, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, K238R, V245E, V276I, E291D, I293V, E312T, I326V, I329V, G335D, R356K, M357K, G359S, K366R, A371V, K390R, K395R, A400T, T403M, E432D, N447S, T470A, D471E, Q480H, H483Y, L491S, D511E, K512R, L517V, S519N, Q524E, A534S, V548I, A554T |
| >AA126a08L| codons 1-560 PISPIDTVPVALKPGMDGPKIKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGTKALTDVVPLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQRETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLAETTNQKTELH AIYLALQDSGSEVNIVTDSQYALGIIQAQPERSESEVVNQIIEELIKKEKVYLSWVPAHK GIGGNEQIDKLVSTGIRKVL |
References
| Author | Title | Citation |
| Rolland, M | Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 | Nature, 2012 |