<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AH-2686 AH-2686 Spain 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ SQV 126

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L Q58E L10I, T12S, K20M, M36I, L63P, A71V  
>AH-2686| codons 1-99
PQITLWQRPIVSIKIGGQLMEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFIKVREYD
QIPIEICGHKVIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Holguin, A Prevalence of human immunodeficiency virus type 1 (HIV-1) Non-B subtypes in foreigners living in Madrid, Spain, and comparison of the performances of the AMPLICOR HIV-1 MONITOR version 1.0 and the new automated version 1.5. J Clin Microbiol, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005