Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S147SG | K14R, L28I, I72V, L101V, T112V, T124A, T125A, G134N, I135V, K136H, V150A, V165I, V201I, K215N, L234I, D253H | S283G |
| >AA099a_WG10| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNIPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFVLKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVHQEFGIPYNPQGQGAVESMNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQNQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQHNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, R41K, R57K, H69K, L89M | K20GR |
| >AA099a_WG10| codons 1-99 PQITLWQRPLVTVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43A, S68G, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R, V245E, V276I, E291D, I293V, A304E, E312T, I326V, I329V, G335D, K347R, K350R, M357K, G359S, K366R, A371V, K385R, K390R, K395R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, Q524E, A534S, A554S, K558R |
| >AA099a_WG10| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEAEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGTKALTDVVPLTEEAE LELEENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFRNLRTGKYARKRSA HTNDVRQLTEVVQKIATESIVIWGRTPKFRLPIQRETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRRVL |
References
| Author | Title | Citation |
| Rolland, M | Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 | Nature, 2012 |