Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89M |
| >AA076a01L| codons 1-99 PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, T39K, K43E, K122E, D123S, K166R, K173I, Q174K, D177E, I178M, T200I, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, I293V, A304E, E312I, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, K390R, K395R, A400T, T403M, E404K, E432D, N447S, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S |
| >AA076a01L| codons 1-560 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDVVPLTEEAE LELEENREILKIPVHGVYYDPSKDLIAEVQKQGQDQWTYQIFQEPFKNLKTGKYARKRSA HTNDVRQLAEAVQKIATESIVIWGKTPKFRLPIQRETWETWWMKYWQATWIPEWEFVNTP PLVKLWYQLEKDPIVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVNQIIEELIKKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, A23V, V31I, S39N, D55N, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136R, V201I, L234I |
| >AA076a01L| codons 1-288 FLDGIDKAQEEHERYHSNWRTMVSDFNLPPIVAKEIVANCDKCQLKGEAMHGQVNCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
References
| Author | Title | Citation |
| Rolland, M | Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 | Nature, 2012 |